{
  "annotation_id": "790afaca-9a16-401d-b0f3-b25c10682b45",
  "date_created": "2026-03-02T18:00:46.237000Z",
  "date_modified": "2026-03-02T18:00:46.237000Z",
  "file_hash": "32ecfa00b3d158ba67d950c0f70b219b4c87d456e0b8971df68a0d6dbbb41a48",
  "private": false,
  "record": {
    "abstract": "We use an instrument combining optical (surface plasmon resonance) and\nacoustic (Love mode acoustic wave device) real-time measurements on a same\nsurface for the identification of water content in collagen and fibrinogen\nprotein layers. After calibration of the surface acoustic wave device\nsensitivity by copper electrodeposition, the bound mass and its physical\nproperties -- density and optical index -- are extracted from the complementary\nmeasurement techniques and lead to thickness and water ratio values compatible\nwith the observed signal shifts. Such results are especially usefully for\nprotein layers with a high water content as shown here for collagen on an\nhydrophobic surface. We obtain the following results: collagen layers include\n70+/-20 % water and are 16+/-3 to 19+/-3 nm thick for bulk concentrations\nranging from 30 to 300 ug/ml. Fibrinogen layers include 50+/-10 % water for\nlayer thicknesses in the 6+/-1.5 to 13+/-2 nm range when the bulk concentration\nis in the 46 to 460 ug/ml range.",
    "arxiv_id": "physics/0310096",
    "authors": [
      "Jean-Michel Friedt",
      "Laurent Francis"
    ],
    "categories": [
      "physics.bio-ph",
      "cond-mat.soft",
      "q-bio.QM"
    ],
    "license": "http://arxiv.org/licenses/nonexclusive-distrib/1.0/",
    "title": "Combined surface acoustic wave and surface plasmon resonance measurement   of collagen and fibrinogen layers",
    "url": "https://arxiv.org/abs/physics/0310096"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "81a48428-3acc-4774-bbdb-841cb32e12ab",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}