{
  "annotation_id": "77e799cd-3deb-4753-9acc-de8272f41c0d",
  "date_created": "2026-03-02T18:01:14.674000Z",
  "date_modified": "2026-03-02T18:01:14.674000Z",
  "file_hash": "c1cd761df563007c96e3d8961381b3f3d91def26ead4dd007f2984f1db51609b",
  "private": false,
  "record": {
    "abstract": "Based on a cellular automaton model the growth kinetics and the critical\nsurface dynamics of cell monolayers is systematically studied by variation of\nthe cell migration activity, the size of the proliferation zone and the cell\ncycle time distribution over wide ranges. The model design avoids lattice\nartifacts and ensures high performance. The monolayer expansion velocity\nderived from our simulations can be interpreted as a generalization of the\nvelocity relationship for a traveling front in the\nFisher-Kolmogorov-Petrovskii-Piskounov (FKPP) equation that is frequently used\nto model tumor growth phenomena by continuum models. The critical surface\ndynamics corresponds to the Kardar-Parisi-Zhang (KPZ) universality class for\nall parameters and model variations studied. While the velocity agrees\nquantitatively with experimental observations by Bru et al, the critical\nsurface dynamics is in contrast to their interpretation as generic\nmolecular-beam-epitaxy-like growth.",
    "arxiv_id": "physics/0610146",
    "authors": [
      "M. Block",
      "E. Schoell",
      "D. Drasdo"
    ],
    "categories": [
      "physics.bio-ph",
      "physics.comp-ph"
    ],
    "doi": "10.1103/PhysRevLett.99.248101",
    "title": "Classifying the expansion kinetics and critical surface dynamics of   growing cell populations",
    "url": "https://arxiv.org/abs/physics/0610146"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "b0da91cf-e4fc-4adb-b97f-3cb795c63f07",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}