{
  "annotation_id": "778b70c7-f824-476a-bab5-06391f826c73",
  "date_created": "2026-03-02T18:00:43.011000Z",
  "date_modified": "2026-03-02T18:00:43.011000Z",
  "file_hash": "bf2c0b2232e97d2c78d41bef1d4baa4cc4d889f5d0d0b790d7236129f0c1f04b",
  "private": false,
  "record": {
    "abstract": "We report Molecular Dynamics (MD) simulations of a generic hydrophobic\nnanopore connecting two reservoirs which are initially at different Na+\nconcentrations, as in a biological cell. The nanopore is impermeable to water\nunder equilibrium conditions, but the strong electric field caused by the ionic\nconcentration gradient drives water molecules in. The density and structure of\nwater in the pore are highly field dependent. In a typical simulation run, we\nobserve a succession of cation passages through the pore, characterized by\napproximately bulk mobility. These ion passages reduce the electric field,\nuntil the pore empties of water and closes to further ion transport, thus\nproviding a possible mechanism for biological ion channel gating.",
    "arxiv_id": "physics/0305135",
    "authors": [
      "J. Dzubiella",
      "R. J. Allen",
      "J. -P. Hansen"
    ],
    "categories": [
      "physics.bio-ph",
      "physics.chem-ph"
    ],
    "doi": "10.1063/1.1665656",
    "journal_ref": "Journal of Chemical Physics 120, 5001 (2004)",
    "title": "Electric field-controlled water permeation coupled to ion transport   through a nanopore",
    "url": "https://arxiv.org/abs/physics/0305135"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "1c443062-0bd2-4db7-bf1f-cfd377090dc3",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}