dorsal/arxiv
View SchemaAutoregulation of the total number of cells in culture
| Authors | A. A. Kozlov |
|---|---|
| Categories | |
| ArXiv ID | physics/0301072 |
| URL | https://arxiv.org/abs/physics/0301072 |
Abstract
According to the universally accepted concept of the development of life on the Earth, multicellular organisms initially emerged as a result of either the union of identical unicellular organisms with the following functional differentiation, or the union of symbionts, in which there already was a certain simple functional separation. However, in either case the progenitors of multicellular organisms were ensembles, communities of unicellular organisms. For a certain number of unicellular organisms to be treated as an ensemble, there must be some interconnection between its members. Colonies of mechanically connected unicellular organisms were a later, more advanced stage; here, unicellular organisms living separately are considered. Such interconnection must, in particular, limit from above the total numbers of the members of the ensemble, because an excessive increase in these numbers could disturb the connections between members of the ensemble to the extent of its destruction. In addition, too large numbers of members in the ensemble could lead to nutrient depletion in its habitat. One can assume that such interconnection between unicellular organisms was evolutionarily developed and genetically fixed. I assumed that modern unicellular organisms retain such an ability to regulate their total numbers. The validity of this assumption was tested in experiments, whose results are presented in this paper.
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"abstract": "According to the universally accepted concept of the development of life on\nthe Earth, multicellular organisms initially emerged as a result of either the\nunion of identical unicellular organisms with the following functional\ndifferentiation, or the union of symbionts, in which there already was a\ncertain simple functional separation. However, in either case the progenitors\nof multicellular organisms were ensembles, communities of unicellular\norganisms. For a certain number of unicellular organisms to be treated as an\nensemble, there must be some interconnection between its members. Colonies of\nmechanically connected unicellular organisms were a later, more advanced stage;\nhere, unicellular organisms living separately are considered. Such\ninterconnection must, in particular, limit from above the total numbers of the\nmembers of the ensemble, because an excessive increase in these numbers could\ndisturb the connections between members of the ensemble to the extent of its\ndestruction. In addition, too large numbers of members in the ensemble could\nlead to nutrient depletion in its habitat. One can assume that such\ninterconnection between unicellular organisms was evolutionarily developed and\ngenetically fixed. I assumed that modern unicellular organisms retain such an\nability to regulate their total numbers. The validity of this assumption was\ntested in experiments, whose results are presented in this paper.",
"arxiv_id": "physics/0301072",
"authors": [
"A. A. Kozlov"
],
"categories": [
"physics.bio-ph",
"q-bio.OT"
],
"title": "Autoregulation of the total number of cells in culture",
"url": "https://arxiv.org/abs/physics/0301072"
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