{
  "annotation_id": "6ba87c02-629e-4d7a-9e5f-a9454acab6b5",
  "date_created": "2026-03-02T18:01:31.348000Z",
  "date_modified": "2026-03-02T18:01:31.348000Z",
  "file_hash": "89ce0e57e04b6204754f513ec4eadcfb48616df9eaba2483f016d6e0396f7407",
  "private": false,
  "record": {
    "abstract": "The Bacillus subtilis Spo0J/Soj proteins, implicated in chromosome\nsegregation and transcriptional regulation, show striking dynamics: Soj\nundergoes irregular relocations from pole to pole or nucleoid to nucleoid. Here\nwe report on a mathematical model of the Soj dynamics. Our model, which is\nclosely based on the available experimental data, readily generates dynamic Soj\nrelocations. We show that the irregularity of the relocations may be due to the\nstochastic nature of the underlying Spo0J/Soj interactions and diffusion. We\npropose explanations for the behavior of several Spo0J/Soj mutants including\nthe \"freezing\" of the Soj dynamics observed in filamentous cells. Our approach\nunderlines the importance of incorporating stochastic effects when modelling\nspatiotemporal protein dynamics inside cells.",
    "arxiv_id": "q-bio/0507007",
    "authors": [
      "Konstantin Doubrovinski",
      "Martin Howard"
    ],
    "categories": [
      "q-bio.SC",
      "cond-mat.stat-mech"
    ],
    "doi": "10.1073/pnas.0500529102",
    "journal_ref": "Proc. Natl. Acad. Sci. 102 9808-9813 (2005)",
    "title": "Stochastic model for Soj relocation dynamics in Bacillus subtilis",
    "url": "https://arxiv.org/abs/q-bio/0507007"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "1641a498-3d54-45c8-8f03-de98bc1f8758",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}