{
  "annotation_id": "6b08468e-ddec-4f8f-8f9e-5ff010d4dec5",
  "date_created": "2026-03-02T18:01:04.334000Z",
  "date_modified": "2026-03-02T18:01:04.334000Z",
  "file_hash": "1ae36ebd1e289314d5218deb21b02ee875fbb7f6f61e3f65374c4e4b627451d0",
  "private": false,
  "record": {
    "abstract": "By representing damage induction by ionizing particles and its repair by the\ncell, the probabilistic two-stage model provides a detailed description of the\nmain processes involved in cell killing by radiation. To link this model with\nissues of interest in hadron radiotherapy, a simple physical model is used.\nEnergy loss, its straggling, and the attenuation of the primary particle\nfluence are represented in a simplified way, based on semi-phenomenological\nformulas and energy-loss tables. An effective version of the radiobiological\nmodel is joined with the simple physical model to estimate cell survival along\nions\u0027 penetration depth. The predicted survival ratios for CHO cells irradiated\nby carbon ions are presented, showing very good agreement with experimental\ndata.",
    "arxiv_id": "physics/0512029",
    "authors": [
      "Pavel Kundr\u00e1t"
    ],
    "categories": [
      "physics.bio-ph",
      "physics.med-ph",
      "q-bio.QM"
    ],
    "title": "Towards biology-oriented treatment planning in hadrontherapy",
    "url": "https://arxiv.org/abs/physics/0512029"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "66669eff-bfc9-4539-ab5b-e94ce9fe8c76",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}