dorsal/arxiv
View SchemaProteomic nonlinear waves in networks of transcriptional regulators
| Authors | A. S. Carstea |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0611042 |
| URL | https://arxiv.org/abs/q-bio/0611042 |
Abstract
A chain of connected genes with activation-repression links is analysed. It is shown that for various promoter activity functions (parametrised by Hill coefficient) the equations describing the concentrations of transcription factors, are differential-difference KdV-type with perturbations. In the case of large Hill coefficient the proteomic signal along the gene network is given by a superposition of perturbed dark solitons of defocusing differential-difference mKdV equation. Biological implications are discussed.
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"abstract": "A chain of connected genes with activation-repression links is analysed. It\nis shown that for various promoter activity functions (parametrised by Hill\ncoefficient) the equations describing the concentrations of transcription\nfactors, are differential-difference KdV-type with perturbations. In the case\nof large Hill coefficient the proteomic signal along the gene network is given\nby a superposition of perturbed dark solitons of defocusing\ndifferential-difference mKdV equation. Biological implications are discussed.",
"arxiv_id": "q-bio/0611042",
"authors": [
"A. S. Carstea"
],
"categories": [
"q-bio.GN"
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"title": "Proteomic nonlinear waves in networks of transcriptional regulators",
"url": "https://arxiv.org/abs/q-bio/0611042"
},
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