dorsal/arxiv
View SchemaPartly melted DNA conformations obtained with a probability peak finding method
| Authors | E. Tostesen |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0404019 |
| URL | https://arxiv.org/abs/q-bio/0404019 |
| DOI | 10.1103/PhysRevE.71.061922 |
| Journal | Phys. Rev. E 71, 061922 (2005) |
Abstract
Peaks in the probabilities of loops or bubbles, helical segments, and unzipping ends in melting DNA are found in this article using a peak finding method that maps the hierarchical structure of certain energy landscapes. The peaks indicate the alternative conformations that coexist in equilibrium and the range of their fluctuations. This yields a representation of the conformational ensemble at a given temperature, which is illustrated in a single diagram called a stitch profile. This article describes the methodology and discusses stitch profiles vs. the ordinary probability profiles using the phage lambda genome as an example.
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"abstract": "Peaks in the probabilities of loops or bubbles, helical segments, and\nunzipping ends in melting DNA are found in this article using a peak finding\nmethod that maps the hierarchical structure of certain energy landscapes. The\npeaks indicate the alternative conformations that coexist in equilibrium and\nthe range of their fluctuations. This yields a representation of the\nconformational ensemble at a given temperature, which is illustrated in a\nsingle diagram called a stitch profile. This article describes the methodology\nand discusses stitch profiles vs. the ordinary probability profiles using the\nphage lambda genome as an example.",
"arxiv_id": "q-bio/0404019",
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"E. Tostesen"
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"doi": "10.1103/PhysRevE.71.061922",
"journal_ref": "Phys. Rev. E 71, 061922 (2005)",
"title": "Partly melted DNA conformations obtained with a probability peak finding method",
"url": "https://arxiv.org/abs/q-bio/0404019"
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