dorsal/arxiv
View SchemaSolitons in Yakushevich-like models of DNA dynamics with improved intrapair potential
| Authors | G. Gaeta |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0604004 |
| URL | https://arxiv.org/abs/q-bio/0604004 |
| DOI | 10.2991/jnmp.2007.14.1.6 |
| Journal | J. Nonlin. Math. Phys. 14 (2007), 57-81 |
Abstract
The Yakushevich (Y) model provides a very simple pictures of DNA torsion dynamics, yet yields remarkably correct predictions on certain physical characteristics of the dynamics. In the standard Y model, the interaction between bases of a pair is modelled by a harmonic potential, which becomes anharmonic when described in terms of the rotation angles; here we substitute to this different types of improved potentials, providing a more physical description of the H-bond mediated interactions between the bases. We focus in particular on soliton solutions; the Y model predicts the correct size of the nonlinear excitations supposed to model the ``transcription bubbles'', and this is essentially unchanged with the improved potential. Other features of soliton dynamics, in particular curvature of soliton field configurations and the Peierls-Nabarro barrier, are instead significantly changed.
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"abstract": "The Yakushevich (Y) model provides a very simple pictures of DNA torsion\ndynamics, yet yields remarkably correct predictions on certain physical\ncharacteristics of the dynamics. In the standard Y model, the interaction\nbetween bases of a pair is modelled by a harmonic potential, which becomes\nanharmonic when described in terms of the rotation angles; here we substitute\nto this different types of improved potentials, providing a more physical\ndescription of the H-bond mediated interactions between the bases. We focus in\nparticular on soliton solutions; the Y model predicts the correct size of the\nnonlinear excitations supposed to model the ``transcription bubbles\u0027\u0027, and this\nis essentially unchanged with the improved potential. Other features of soliton\ndynamics, in particular curvature of soliton field configurations and the\nPeierls-Nabarro barrier, are instead significantly changed.",
"arxiv_id": "q-bio/0604004",
"authors": [
"G. Gaeta"
],
"categories": [
"q-bio.BM"
],
"doi": "10.2991/jnmp.2007.14.1.6",
"journal_ref": "J. Nonlin. Math. Phys. 14 (2007), 57-81",
"title": "Solitons in Yakushevich-like models of DNA dynamics with improved intrapair potential",
"url": "https://arxiv.org/abs/q-bio/0604004"
},
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