dorsal/arxiv
View SchemaPhase diagram of a ternary mixture of cholesterol and saturated and unsaturated lipids calculated from a microscopic model
| Authors | R. Elliott, I. Szleifer, M. Schick |
|---|---|
| Categories | |
| ArXiv ID | physics/0508011 |
| URL | https://arxiv.org/abs/physics/0508011 |
| DOI | 10.1103/PhysRevLett.96.098101 |
| Journal | Published in Physical Review Letters, 96, 098101 (2006). |
Abstract
We employ a molecular model to study a ternary mixture of saturated lipid, with tails of sixteen carbons, a mono unsaturated lipid with tails of eighteen carbons, and cholesterol. The model, solved within mean-field theory, produces several forms of phase diagrams depending upon the relative strengths of interactions, but only one that shows the coexistence of two liquid phases observed in experiment. The lipids in the phase rich in cholesterol are more ordered than those in the other. The binary cholesterol, saturated lipid system also exhibits liquid, liquid coexistence.
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"abstract": "We employ a molecular model to study a ternary mixture of saturated lipid,\nwith tails of sixteen carbons, a mono unsaturated lipid with tails of eighteen\ncarbons, and cholesterol. The model, solved within mean-field theory, produces\nseveral forms of phase diagrams depending upon the relative strengths of\ninteractions, but only one that shows the coexistence of two liquid phases\nobserved in experiment. The lipids in the phase rich in cholesterol are more\nordered than those in the other. The binary cholesterol, saturated lipid system\nalso exhibits liquid, liquid coexistence.",
"arxiv_id": "physics/0508011",
"authors": [
"R. Elliott",
"I. Szleifer",
"M. Schick"
],
"categories": [
"physics.bio-ph"
],
"doi": "10.1103/PhysRevLett.96.098101",
"journal_ref": "Published in Physical Review Letters, 96, 098101 (2006).",
"title": "Phase diagram of a ternary mixture of cholesterol and saturated and unsaturated lipids calculated from a microscopic model",
"url": "https://arxiv.org/abs/physics/0508011"
},
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