dorsal/arxiv
View SchemaThe astrocyte as a gatekeeper of synaptic information transfer
| Authors | Vladislav Volman, Eshel Ben-Jacob, Herbert Levine |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0612014 |
| URL | https://arxiv.org/abs/q-bio/0612014 |
Abstract
We present a simple biophysical model for the coupling between synaptic transmission and the local calcium concentration on an enveloping astrocytic domain. This interaction enables the astrocyte to modulate the information flow from presynaptic to postsynaptic cells in a manner dependent on previous activity at this and other nearby synapses. Our model suggests a novel, testable hypothesis for the spike timing statistics measured for rapidly-firing cells in culture experiments.
{
"annotation_id": "5e406e10-5a11-4374-8955-fd2a0b1e8e44",
"date_created": "2026-03-02T18:01:34.734000Z",
"date_modified": "2026-03-02T18:01:34.734000Z",
"file_hash": "89528a261b7158d4c681cc61cf03647c094762d16f86868766eaaa4d51b4e647",
"private": false,
"record": {
"abstract": "We present a simple biophysical model for the coupling between synaptic\ntransmission and the local calcium concentration on an enveloping astrocytic\ndomain. This interaction enables the astrocyte to modulate the information flow\nfrom presynaptic to postsynaptic cells in a manner dependent on previous\nactivity at this and other nearby synapses. Our model suggests a novel,\ntestable hypothesis for the spike timing statistics measured for rapidly-firing\ncells in culture experiments.",
"arxiv_id": "q-bio/0612014",
"authors": [
"Vladislav Volman",
"Eshel Ben-Jacob",
"Herbert Levine"
],
"categories": [
"q-bio.NC"
],
"title": "The astrocyte as a gatekeeper of synaptic information transfer",
"url": "https://arxiv.org/abs/q-bio/0612014"
},
"schema_id": "dorsal/arxiv",
"source": {
"execution_id": "12fa81ab-6bfd-4cf2-a84f-e29d84a81429",
"id": "arXiv Dataset IDs",
"type": "Model",
"variant": "snapshot-2026-03-01",
"version": "0.1.0"
},
"user_id": 1000002
}