dorsal/arxiv
View SchemaProbability distribution of bubble lengths in DNA
| Authors | S. Ares, G. Kalosakas |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0607009 |
| URL | https://arxiv.org/abs/q-bio/0607009 |
| DOI | 10.1021/nl062304a |
| Journal | Nano Lett., 7 (2), 307 -311, 2007 |
Abstract
The distribution of bubble lengths in double-stranded DNA is presented for segments of varying guanine-cytosine (GC) content, obtained with Monte Carlo simulations using the Peyrard-Bishop-Dauxois model at 310 K. An analytical description of the obtained distribution in the whole regime investigated, i.e., up to bubble widths of the order of tens of nanometers, is available. We find that the decay lengths and characteristic exponents of this distribution show two distinct regimes as a function of GC content. The observed distribution is attributed to the anharmonic interactions within base pairs. The results are discussed in the framework of the Poland-Scheraga and the Peyrard-Bishop (with linear instead of nonlinear stacking interaction) models.
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"abstract": "The distribution of bubble lengths in double-stranded DNA is presented for\nsegments of varying guanine-cytosine (GC) content, obtained with Monte Carlo\nsimulations using the Peyrard-Bishop-Dauxois model at 310 K. An analytical\ndescription of the obtained distribution in the whole regime investigated,\ni.e., up to bubble widths of the order of tens of nanometers, is available. We\nfind that the decay lengths and characteristic exponents of this distribution\nshow two distinct regimes as a function of GC content. The observed\ndistribution is attributed to the anharmonic interactions within base pairs.\nThe results are discussed in the framework of the Poland-Scheraga and the\nPeyrard-Bishop (with linear instead of nonlinear stacking interaction) models.",
"arxiv_id": "q-bio/0607009",
"authors": [
"S. Ares",
"G. Kalosakas"
],
"categories": [
"q-bio.BM",
"cond-mat.stat-mech",
"physics.bio-ph"
],
"doi": "10.1021/nl062304a",
"journal_ref": "Nano Lett., 7 (2), 307 -311, 2007",
"title": "Probability distribution of bubble lengths in DNA",
"url": "https://arxiv.org/abs/q-bio/0607009"
},
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