dorsal/arxiv
View Schema3He Lung Imaging in an Open Access, Very-Low-Field Human MRI System
| Authors | R. W. Mair, M. I. Hrovat, S. Patz, M. S. Rosen, I. C. Ruset, G. P. Topulos, L. L. Tsai, J. P. Butler, F. W. Hersman, R. L. Walsworth |
|---|---|
| Categories | |
| ArXiv ID | physics/0403090 |
| URL | https://arxiv.org/abs/physics/0403090 |
Abstract
The human lung and its functions are extremely sensitive to gravity, however the conventional high-field magnets used for most laser-polarized 3He MRI of the human lung restrict subjects to lying horizontally. Imaging of human lungs using inhaled laser-polarized 3He gas is demonstrated in an open-access very-low-magnetic-field (< 5 mT) MRI instrument. This prototype device employs a simple, low-cost electromagnet, with an open geometry that allows variation of the orientation of the imaging subject in a two-dimensional plane. As a demonstration, two-dimensional lung images were acquired with 4 mm in-plane resolution from a subject in two orientations: lying supine, and sitting in a vertical position with one arm raised. Experience with this prototype device will guide optimization of a second-generation very-low-field imager to enable studies of human pulmonary physiology as a function of subject orientation.
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"abstract": "The human lung and its functions are extremely sensitive to gravity, however\nthe conventional high-field magnets used for most laser-polarized 3He MRI of\nthe human lung restrict subjects to lying horizontally. Imaging of human lungs\nusing inhaled laser-polarized 3He gas is demonstrated in an open-access\nvery-low-magnetic-field (\u003c 5 mT) MRI instrument. This prototype device employs\na simple, low-cost electromagnet, with an open geometry that allows variation\nof the orientation of the imaging subject in a two-dimensional plane. As a\ndemonstration, two-dimensional lung images were acquired with 4 mm in-plane\nresolution from a subject in two orientations: lying supine, and sitting in a\nvertical position with one arm raised. Experience with this prototype device\nwill guide optimization of a second-generation very-low-field imager to enable\nstudies of human pulmonary physiology as a function of subject orientation.",
"arxiv_id": "physics/0403090",
"authors": [
"R. W. Mair",
"M. I. Hrovat",
"S. Patz",
"M. S. Rosen",
"I. C. Ruset",
"G. P. Topulos",
"L. L. Tsai",
"J. P. Butler",
"F. W. Hersman",
"R. L. Walsworth"
],
"categories": [
"physics.med-ph",
"physics.ins-det"
],
"title": "3He Lung Imaging in an Open Access, Very-Low-Field Human MRI System",
"url": "https://arxiv.org/abs/physics/0403090"
},
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