dorsal/arxiv
View SchemaExploring DNA translocation through a nanopore via a multiscale Lattice-Boltzmann Molecular-Dynamics methodology
| Authors | Simone Melchionna, Maria Fyta, Efthimios Kaxiras, Sauro Succi |
|---|---|
| Categories | |
| ArXiv ID | physics/0702180 |
| URL | https://arxiv.org/abs/physics/0702180 |
| DOI | 10.1142/S0129183107010942 |
| Journal | Int. J. Mod. Phys. C, 18 685 (2007) |
Abstract
A multiscale approach is used to simulate the translocation of DNA through a nanopore. Within this scheme, the interactions of the molecule with the surrounding fluid (solvent) are explicitly taken into account. By generating polymers of various initial configurations and lengths we map the probability distibutions of the passage times of the DNA through the nanopore. A scaling law behavior for the most probable of these times with respect to length is derived, and shown to exhibit an exponent that is in a good agreement with the experimental findings. The essential features of the DNA dynamics as it passes through the pore are explored.
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"abstract": "A multiscale approach is used to simulate the translocation of DNA through a\nnanopore. Within this scheme, the interactions of the molecule with the\nsurrounding fluid (solvent) are explicitly taken into account. By generating\npolymers of various initial configurations and lengths we map the probability\ndistibutions of the passage times of the DNA through the nanopore. A scaling\nlaw behavior for the most probable of these times with respect to length is\nderived, and shown to exhibit an exponent that is in a good agreement with the\nexperimental findings. The essential features of the DNA dynamics as it passes\nthrough the pore are explored.",
"arxiv_id": "physics/0702180",
"authors": [
"Simone Melchionna",
"Maria Fyta",
"Efthimios Kaxiras",
"Sauro Succi"
],
"categories": [
"physics.bio-ph"
],
"doi": "10.1142/S0129183107010942",
"journal_ref": "Int. J. Mod. Phys. C, 18 685 (2007)",
"title": "Exploring DNA translocation through a nanopore via a multiscale Lattice-Boltzmann Molecular-Dynamics methodology",
"url": "https://arxiv.org/abs/physics/0702180"
},
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