{
  "annotation_id": "566a8009-3d1f-449f-b53e-29a4570a07d3",
  "date_created": "2026-03-02T18:00:50.440000Z",
  "date_modified": "2026-03-02T18:00:50.440000Z",
  "file_hash": "7facaca283c7cabcde4bd218f1a171f207a6e10a7eb5d82f55e47531753a5e2e",
  "private": false,
  "record": {
    "abstract": "Irradiation of cell monolayers by monoenergetic ions has made it possible to\nestablish survival curves at individual values of linear energy transfer. The\ntwo-step model of radiobiological mechanism proposed recently by Judas and\nLokajicek (Judas L., Lokajicek M., 2001: Cell inactivation by ionizing\nparticles and the shapes of survival curves. J. Theor. Biol. 210 (1), 15-21.,\ndoi:10.1006/jtbi.2001.2283) has then enabled to show that some significant\ndeviations from the generally used linear-quadratic model should exist at\nhigher values of linear energy transfer, which has been also demonstrated\nexperimentally. However, the new model has been expressed in the form being\napplicable rightfully to low-dose parts of survival curves only. It has been\nnow reformulated to be applicable in analyses of whole survival curves.\nInactivation probabilities after different numbers of particles traversing cell\nnuclei (chromosomal systems) may be then derived from experimental data.\nAnalyses of published data obtained in irradiating by protons and deuterons\nwill be presented and discussed.",
    "arxiv_id": "physics/0407043",
    "authors": [
      "Pavel Kundrat",
      "Milos Lokajicek",
      "Hana Hromcikova"
    ],
    "categories": [
      "physics.med-ph",
      "physics.bio-ph",
      "q-bio.QM"
    ],
    "title": "Cell inactivation by diverse ions along their tracks",
    "url": "https://arxiv.org/abs/physics/0407043"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "e82b9c8f-04ff-4062-9b31-836362e058a3",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}