dorsal/arxiv
View SchemaA protein structural alphabet and its substitution matrix CLESUM
| Authors | Wei-Mou Zheng, Xin Liu |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0412046 |
| URL | https://arxiv.org/abs/q-bio/0412046 |
Abstract
By using a mixture model for the density distribution of the three pseudobond angles formed by $C_\alpha$ atoms of four consecutive residues, the local structural states are discretized as 17 conformational letters of a protein structural alphabet. This coarse-graining procedure converts a 3D structure to a 1D code sequence. A substitution matrix between these letters is constructed based on the structural alignments of the FSSP database.
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"abstract": "By using a mixture model for the density distribution of the three pseudobond\nangles formed by $C_\\alpha$ atoms of four consecutive residues, the local\nstructural states are discretized as 17 conformational letters of a protein\nstructural alphabet. This coarse-graining procedure converts a 3D structure to\na 1D code sequence. A substitution matrix between these letters is constructed\nbased on the structural alignments of the FSSP database.",
"arxiv_id": "q-bio/0412046",
"authors": [
"Wei-Mou Zheng",
"Xin Liu"
],
"categories": [
"q-bio.BM"
],
"title": "A protein structural alphabet and its substitution matrix CLESUM",
"url": "https://arxiv.org/abs/q-bio/0412046"
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