{
  "annotation_id": "53b95bfa-eeeb-4c9b-bd08-5142149bcabb",
  "date_created": "2026-03-02T18:00:32.485000Z",
  "date_modified": "2026-03-02T18:00:32.485000Z",
  "file_hash": "3e089296aebadfe7d3184bae8dd7df39f7c90f46db354a96ab5c57f11310e289",
  "private": false,
  "record": {
    "abstract": "We study the evolution of mutation rates for an asexual population living on\na static fitness landscape, consisting of multiple peaks forming an\nevolutionary staircase. The optimal mutation rate is found by maximizing the\ndiffusion towards higher fitness. Surprisingly the optimal genomic copying\nfidelity is given by Q = e^(-1/ln(n)) (where n is the genome length),\nindependent of all other parameters in the model. Simulations confirm this\ntheoretical result. We also discuss the relation between the optimal mutation\nrate on static and dynamic fitness landscapes.",
    "arxiv_id": "physics/0005018",
    "authors": [
      "M. Nilsson"
    ],
    "categories": [
      "physics.bio-ph",
      "q-bio"
    ],
    "title": "Optimal Mutation Rates on Static Fitness Landscpes",
    "url": "https://arxiv.org/abs/physics/0005018"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "b8ea882f-11ce-41f4-8903-6c5c3886b9b8",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}