{
  "annotation_id": "4d2249fe-1d1d-4240-a7b7-1eab4acc317a",
  "date_created": "2026-03-02T18:01:34.799000Z",
  "date_modified": "2026-03-02T18:01:34.799000Z",
  "file_hash": "83c0df8532cedb104bb74b2918ee0798a8028cbd2f75f60db91d2afe62ad61c1",
  "private": false,
  "record": {
    "abstract": "The effect of environmental temperature on neuronal spiking behaviors is\ninvestigated by numerically simulating the temperature dependence of spiking\nthreshold of the Hodgkin-Huxley neuron subject to synaptic stimulus. We find\nthat the spiking threshold exhibits a global minimum in a \"comfortable\ntemperature\" range where spike initiation needs weakest synaptic strength,\nindicating the occurrence of optimal use of synaptic transmission in neural\nsystem. We further explore the biophysical origin of this phenomenon in ion\nchannel gating kinetics and also discuss its possible biological relevance in\ninformation processing in neural systems.",
    "arxiv_id": "q-bio/0703017",
    "authors": [
      "Shenbing Kuang",
      "Jiafu Wang",
      "Ting Zeng",
      "Aiyin Cao"
    ],
    "categories": [
      "q-bio.NC"
    ],
    "doi": "10.1007/s12043-008-0016-1",
    "title": "Thermal Impact on Spiking Properties in Hodgkin-Huxley Neuron with   Synaptic Stimulus",
    "url": "https://arxiv.org/abs/q-bio/0703017"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "889237a1-ec54-468b-9cd5-5fb4bd60fa25",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}