dorsal/arxiv
View SchemaBacteriophage-mediated competition in Bordetella bacteria
| Authors | Jaewook Joo, Michelle Gunny, Marisa Cases, Peter Hudson, Reka Albert, Eric Harvill |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0507038 |
| URL | https://arxiv.org/abs/q-bio/0507038 |
| DOI | 10.1098/rspb.2006.3512 |
| Journal | Proceedings of the Royal Society B: Biological Sciences (2006) |
Abstract
Apparent competition between species is believed to be one of the principle driving forces that structure ecological communities, although the precise mecha nisms have yet to be characterized. Here we develop a model system that isolates phage-mediated interactions by neutralizing resource competition using two genetically identical Bordetella bronchiseptica strains that differ only in that one is the carrier of a phage and the other is susceptible to the phage. We observe and quantify the competitive advantage of the bacterial strain bearing the prophage in both invading and in resisting invasion by bacteria susceptible to the phage, and use our measurements to develop a mathematical model of phage-mediated competition. The model predicts, and experimental evidence confirms, that the competitive advantage conferred by the phage depends only on the relative phage pathology and is independent of other phage and host parameters. This work combines experimental and mathematical approaches to the study of phage-driven competition, and provides an experimentally tested framework for evaluation of the effects of pathogens/parasites on interspecific competition.
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"abstract": "Apparent competition between species is believed to be one of the principle\ndriving forces that structure ecological communities, although the precise\nmecha nisms have yet to be characterized. Here we develop a model system that\nisolates phage-mediated interactions by neutralizing resource competition using\ntwo genetically identical Bordetella bronchiseptica strains that differ only in\nthat one is the carrier of a phage and the other is susceptible to the phage.\nWe observe and quantify the competitive advantage of the bacterial strain\nbearing the prophage in both invading and in resisting invasion by bacteria\nsusceptible to the phage, and use our measurements to develop a mathematical\nmodel of phage-mediated competition. The model predicts, and experimental\nevidence confirms, that the competitive advantage conferred by the phage\ndepends only on the relative phage pathology and is independent of other phage\nand host parameters. This work combines experimental and mathematical\napproaches to the study of phage-driven competition, and provides an\nexperimentally tested framework for evaluation of the effects of\npathogens/parasites on interspecific competition.",
"arxiv_id": "q-bio/0507038",
"authors": [
"Jaewook Joo",
"Michelle Gunny",
"Marisa Cases",
"Peter Hudson",
"Reka Albert",
"Eric Harvill"
],
"categories": [
"q-bio.PE"
],
"doi": "10.1098/rspb.2006.3512",
"journal_ref": "Proceedings of the Royal Society B: Biological Sciences (2006)",
"title": "Bacteriophage-mediated competition in Bordetella bacteria",
"url": "https://arxiv.org/abs/q-bio/0507038"
},
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