dorsal/arxiv
View SchemaCoupled dynamics of RNA folding and nanopore translocation
| Authors | Ralf Bundschuh, Ulrich Gerland |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0508004 |
| URL | https://arxiv.org/abs/q-bio/0508004 |
| DOI | 10.1103/PhysRevLett.95.208104 |
Abstract
The translocation of structured RNA or DNA molecules through narrow pores necessitates the opening of all base pairs. Here, we study the interplay between the dynamics of translocation and base-pairing theoretically, using kinetic Monte Carlo simulations and analytical methods. We find that the transient formation of basepairs that do not occur in the ground state can significantly speed up translocation.
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"abstract": "The translocation of structured RNA or DNA molecules through narrow pores\nnecessitates the opening of all base pairs. Here, we study the interplay\nbetween the dynamics of translocation and base-pairing theoretically, using\nkinetic Monte Carlo simulations and analytical methods. We find that the\ntransient formation of basepairs that do not occur in the ground state can\nsignificantly speed up translocation.",
"arxiv_id": "q-bio/0508004",
"authors": [
"Ralf Bundschuh",
"Ulrich Gerland"
],
"categories": [
"q-bio.BM",
"cond-mat.soft"
],
"doi": "10.1103/PhysRevLett.95.208104",
"title": "Coupled dynamics of RNA folding and nanopore translocation",
"url": "https://arxiv.org/abs/q-bio/0508004"
},
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