{
  "annotation_id": "43484fd1-4fbf-4eb8-be02-9d2b58af4671",
  "date_created": "2026-03-02T18:01:35.489000Z",
  "date_modified": "2026-03-02T18:01:35.489000Z",
  "file_hash": "b8f3fdeea05e1f7de50fb53653d5e12f56a9dd0ff315b620fa36654f639b5f38",
  "private": false,
  "record": {
    "abstract": "We study the fluctuation dynamics of localized denaturation bubbles in\nheteropolymer DNA with a master equation and complementary stochastic\nsimulation based on novel DNA stability data. A significant dependence of\nopening probability and waiting time between bubble events on the local DNA\nsequence is revealed and quantified for a biological sequence of the T7\nbacteriophage. Quantitative agreement with data from fluorescence correlation\nspectroscopy (FCS) is demonstrated.",
    "arxiv_id": "q-bio/0608036",
    "authors": [
      "Tobias Ambjornsson",
      "Suman K. Banik",
      "Oleg Krichevsky",
      "Ralf Metzler"
    ],
    "categories": [
      "q-bio.BM",
      "cond-mat.stat-mech"
    ],
    "doi": "10.1103/PhysRevLett.97.128105",
    "title": "Sequence sensitivity of breathing dynamics in heteropolymer DNA",
    "url": "https://arxiv.org/abs/q-bio/0608036"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "ec9db304-20ba-439a-bf5a-3280cb2c580e",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}