{
  "annotation_id": "3d57f9c7-441a-49b9-8058-18750c2eff91",
  "date_created": "2026-03-02T18:01:35.823000Z",
  "date_modified": "2026-03-02T18:01:35.823000Z",
  "file_hash": "dae1bec01a29bd8c0797ae875c5458015fa51dcb0e46f17eb4aae4bfb443bfb5",
  "private": false,
  "record": {
    "abstract": "Microtubules (MTs) are important cytoskeletal structures, engaged in a number\nof specific cellular activities, including vesicular traffic, cell\ncyto-architecture and motility, cell division, and information processing\nwithin neuronal processes. MTs have also been implicated in higher neuronal\nfunctions, including memory, and the emergence of \"consciousness\". How MTs\nhandle and process electrical information, however, is heretofore unknown. Here\nwe show new electrodynamic properties of MTs. Isolated, taxol-stabilized\nmicrotubules behave as bio-molecular transistors capable of amplifying\nelectrical information. Electrical amplification by MTs can lead to the\nenhancement of dynamic information, and processivity in neurons can be\nconceptualized as an \"ionic-based\" transistor, which may impact among other\nknown functions, neuronal computational capabilities.",
    "arxiv_id": "q-bio/0606009",
    "authors": [
      "Avner Priel",
      "Arnolt J. Ramos",
      "Jack A. Tuszynski",
      "Horacio F. Cantiello"
    ],
    "categories": [
      "q-bio.SC",
      "q-bio.BM"
    ],
    "doi": "10.1529/biophysj.105.078915",
    "journal_ref": "Biophys. J. 2006 90: 4639-4643",
    "title": "A Bio-Polymer Transistor: Electrical Amplification by Microtubules",
    "url": "https://arxiv.org/abs/q-bio/0606009"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "570f6fd5-68d0-4a20-b9b2-6423e8dacfc1",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}