dorsal/arxiv
View SchemaInformation theory, multivariate dependence, and genetic network inference
| Authors | Ilya Nemenman |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0406015 |
| URL | https://arxiv.org/abs/q-bio/0406015 |
Abstract
We define the concept of dependence among multiple variables using maximum entropy techniques and introduce a graphical notation to denote the dependencies. Direct inference of information theoretic quantities from data uncovers dependencies even in undersampled regimes when the joint probability distribution cannot be reliably estimated. The method is tested on synthetic data. We anticipate it to be useful for inference of genetic circuits and other biological signaling networks.
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"abstract": "We define the concept of dependence among multiple variables using maximum\nentropy techniques and introduce a graphical notation to denote the\ndependencies. Direct inference of information theoretic quantities from data\nuncovers dependencies even in undersampled regimes when the joint probability\ndistribution cannot be reliably estimated. The method is tested on synthetic\ndata. We anticipate it to be useful for inference of genetic circuits and other\nbiological signaling networks.",
"arxiv_id": "q-bio/0406015",
"authors": [
"Ilya Nemenman"
],
"categories": [
"q-bio.QM",
"cs.IT",
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"math.ST",
"physics.data-an",
"q-bio.GN",
"stat.TH"
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"title": "Information theory, multivariate dependence, and genetic network inference",
"url": "https://arxiv.org/abs/q-bio/0406015"
},
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