{
  "annotation_id": "34b7a398-23ca-4a8f-bdc6-7899d2969bac",
  "date_created": "2026-03-02T18:00:39.604000Z",
  "date_modified": "2026-03-02T18:00:39.604000Z",
  "file_hash": "e446168b8a2be2b44417fe0dc22010937a3d08c967076b3b1b7e31450a18acd2",
  "private": false,
  "record": {
    "abstract": "The specific morphology of germinal centers is analyzed in the context of the\noptimization of the humoral immune response. The relevance of dark and light\nzones for the affinity maturation process is investigated in the framework of a\ntheoretical model for the germinal center reaction. Especially, it is shown\nthat an intermediate appearance of dark zones in germinal center reactions is\nadvantageous for the process of antibody optimization. Methodological aspects\nare discussed.",
    "arxiv_id": "physics/0203045",
    "authors": [
      "Michael Meyer-Hermann"
    ],
    "categories": [
      "physics.bio-ph",
      "q-bio.CB"
    ],
    "title": "The relation of morphology and affinity maturation in germinal centers",
    "url": "https://arxiv.org/abs/physics/0203045"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "7659bde0-38b0-45fb-b24f-8553fd32e76e",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}