dorsal/arxiv
View SchemaPeptide size dependent active transport in the proteasome
| Authors | Alexei Zaikin, Thorsten Poeschel |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0311036 |
| URL | https://arxiv.org/abs/q-bio/0311036 |
Abstract
We investigate the transport of proteins inside the proteasome and propose an active transport mechanism based on a spatially asymmetric interaction potential of peptide chains. The transport is driven by fluctuations which are always present in such systems. We compute the peptide-size dependent transport rate which is essential for the functioning of the proteasome. In agreement with recent experiments, varying temperature changes the transport mechanism qualitatively.
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"abstract": "We investigate the transport of proteins inside the proteasome and propose an\nactive transport mechanism based on a spatially asymmetric interaction\npotential of peptide chains. The transport is driven by fluctuations which are\nalways present in such systems. We compute the peptide-size dependent transport\nrate which is essential for the functioning of the proteasome. In agreement\nwith recent experiments, varying temperature changes the transport mechanism\nqualitatively.",
"arxiv_id": "q-bio/0311036",
"authors": [
"Alexei Zaikin",
"Thorsten Poeschel"
],
"categories": [
"q-bio.BM",
"cond-mat.soft"
],
"title": "Peptide size dependent active transport in the proteasome",
"url": "https://arxiv.org/abs/q-bio/0311036"
},
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