dorsal/arxiv
View SchemaTransporting of a Cell-Sized Phospholipid Vesicle Across Water/Oil Interface
| Authors | Masahiko Hase, Ayako Yamada, Tsutomu Hamada, Kenichi Yoshikawa |
|---|---|
| Categories | |
| ArXiv ID | physics/0601015 |
| URL | https://arxiv.org/abs/physics/0601015 |
| DOI | 10.1016/j.cplett.2006.06.016 |
Abstract
When a cell-sized water droplet, with a diameter of several tens of micro meter, is placed in oil containing phospholipids, a stable cell-sized vesicle is spontaneously formed as a water-in-oil phospholipid emulsion (W/O CE) with a phospholipid monolayer. We transferred the lipid vesicle thus formed in the oil phase to the water phase across the water/oil interface by micromanipulation, which suggests that the vesicle is transformed from a phospholipid monolayer as W/O CE into a bilayer. The lipid vesicle can then be transported back into the oil phase. This novel experimental procedure may be a useful tool for creating a model cellular system, which, together with a microreactor, is applicable as a micrometer-scale biochemical reaction field.
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"abstract": "When a cell-sized water droplet, with a diameter of several tens of micro\nmeter, is placed in oil containing phospholipids, a stable cell-sized vesicle\nis spontaneously formed as a water-in-oil phospholipid emulsion (W/O CE) with a\nphospholipid monolayer. We transferred the lipid vesicle thus formed in the oil\nphase to the water phase across the water/oil interface by micromanipulation,\nwhich suggests that the vesicle is transformed from a phospholipid monolayer as\nW/O CE into a bilayer. The lipid vesicle can then be transported back into the\noil phase. This novel experimental procedure may be a useful tool for creating\na model cellular system, which, together with a microreactor, is applicable as\na micrometer-scale biochemical reaction field.",
"arxiv_id": "physics/0601015",
"authors": [
"Masahiko Hase",
"Ayako Yamada",
"Tsutomu Hamada",
"Kenichi Yoshikawa"
],
"categories": [
"physics.chem-ph",
"physics.bio-ph"
],
"doi": "10.1016/j.cplett.2006.06.016",
"title": "Transporting of a Cell-Sized Phospholipid Vesicle Across Water/Oil Interface",
"url": "https://arxiv.org/abs/physics/0601015"
},
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