dorsal/arxiv
View SchemaLeave-one-out prediction error of systolic arterial pressure time series under paced breathing
| Authors | N. Ancona, R. Maestri, D. Marinazzo, L. Nitti, M. Pellicoro, G. D. Pinna, S. Stramaglia |
|---|---|
| Categories | |
| ArXiv ID | physics/0411206 |
| URL | https://arxiv.org/abs/physics/0411206 |
| DOI | 10.1088/0967-3334/26/4/003 |
Abstract
In this paper we show that different physiological states and pathological conditions may be characterized in terms of predictability of time series signals from the underlying biological system. In particular we consider systolic arterial pressure time series from healthy subjects and Chronic Heart Failure patients, undergoing paced respiration. We model time series by the regularized least squares approach and quantify predictability by the leave-one-out error. We find that the entrainment mechanism connected to paced breath, that renders the arterial blood pressure signal more regular, thus more predictable, is less effective in patients, and this effect correlates with the seriousness of the heart failure. The leave-one-out error separates controls from patients and, when all orders of nonlinearity are taken into account, alive patients from patients for which cardiac death occurred.
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"abstract": "In this paper we show that different physiological states and pathological\nconditions may be characterized in terms of predictability of time series\nsignals from the underlying biological system. In particular we consider\nsystolic arterial pressure time series from healthy subjects and Chronic Heart\nFailure patients, undergoing paced respiration. We model time series by the\nregularized least squares approach and quantify predictability by the\nleave-one-out error. We find that the entrainment mechanism connected to paced\nbreath, that renders the arterial blood pressure signal more regular, thus more\npredictable, is less effective in patients, and this effect correlates with the\nseriousness of the heart failure. The leave-one-out error separates controls\nfrom patients and, when all orders of nonlinearity are taken into account,\nalive patients from patients for which cardiac death occurred.",
"arxiv_id": "physics/0411206",
"authors": [
"N. Ancona",
"R. Maestri",
"D. Marinazzo",
"L. Nitti",
"M. Pellicoro",
"G. D. Pinna",
"S. Stramaglia"
],
"categories": [
"physics.med-ph",
"physics.bio-ph",
"q-bio.QM"
],
"doi": "10.1088/0967-3334/26/4/003",
"title": "Leave-one-out prediction error of systolic arterial pressure time series under paced breathing",
"url": "https://arxiv.org/abs/physics/0411206"
},
"schema_id": "dorsal/arxiv",
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