{
  "annotation_id": "2c654816-8a18-4792-8511-4af68eff9f4c",
  "date_created": "2026-03-02T18:01:04.222000Z",
  "date_modified": "2026-03-02T18:01:04.222000Z",
  "file_hash": "1a26fef32cacc7a0d2210738daa995e1d1e991fec17c44886b819ef0f7aa3580",
  "private": false,
  "record": {
    "abstract": "An integrated microscope that combines different optical techniques for\nsimultaneous imaging is demonstrated. The microscope enables spectral-domain\noptical coherence microscopy based on optical backscatter, and multi-photon\nmicroscopy for the detection of two-photon fluorescence and second harmonic\ngeneration signals. The unique configuration of this integrated microscope\nallows for the simultaneous acquisition of both anatomical (structural) and\nfunctional imaging information with particular emphasis for applications in the\nfields of tissue engineering and cell biology. In addition, the contemporary\nanalysis of the spectroscopic features can enhance contrast by differentiating\namong different tissue components.",
    "arxiv_id": "physics/0512161",
    "authors": [
      "C. Vinegoni",
      "T. Ralston",
      "W. Tan",
      "W. Luo",
      "D. L. Marks",
      "S. A. Boppart"
    ],
    "categories": [
      "physics.optics",
      "physics.med-ph"
    ],
    "doi": "10.1063/1.2171477",
    "title": "Integrated structural and functional optical imaging combining   spectral-domain optical coherence and multiphoton microscopy",
    "url": "https://arxiv.org/abs/physics/0512161"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "936ee779-3296-4cc6-b136-ff7b5a33d9e0",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}