dorsal/arxiv
View SchemaThe Force-Velocity Relation for Growing Biopolymers
| Authors | A. E. Carlsson |
|---|---|
| Categories | |
| ArXiv ID | physics/0003038 |
| URL | https://arxiv.org/abs/physics/0003038 |
| DOI | 10.1103/PhysRevE.62.7082 |
Abstract
The process of force generation by the growth of biopolymers is simulated via a Langevin-dynamics approach. The interaction forces are taken to have simple forms that favor the growth of straight fibers from solution. The force-velocity relation is obtained from the simulations for two versions of the monomer-monomer force field. It is found that the growth rate drops off more rapidly with applied force than expected from the simplest theories based on thermal motion of the obstacle. The discrepancies amount to a factor of three or more when the applied force exceeds 2.5kT/a, where a is the step size for the polymer growth. These results are explained on the basis of restricted diffusion of monomers near the fiber tip. It is also found that the mobility of the obstacle has little effect on the growth rate, over a broad range.
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"abstract": "The process of force generation by the growth of biopolymers is simulated via\na Langevin-dynamics approach. The interaction forces are taken to have simple\nforms that favor the growth of straight fibers from solution. The\nforce-velocity relation is obtained from the simulations for two versions of\nthe monomer-monomer force field. It is found that the growth rate drops off\nmore rapidly with applied force than expected from the simplest theories based\non thermal motion of the obstacle. The discrepancies amount to a factor of\nthree or more when the applied force exceeds 2.5kT/a, where a is the step size\nfor the polymer growth. These results are explained on the basis of restricted\ndiffusion of monomers near the fiber tip. It is also found that the mobility of\nthe obstacle has little effect on the growth rate, over a broad range.",
"arxiv_id": "physics/0003038",
"authors": [
"A. E. Carlsson"
],
"categories": [
"physics.bio-ph",
"cond-mat",
"physics.comp-ph"
],
"doi": "10.1103/PhysRevE.62.7082",
"title": "The Force-Velocity Relation for Growing Biopolymers",
"url": "https://arxiv.org/abs/physics/0003038"
},
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