{
  "annotation_id": "265ee5eb-22a9-4424-bca5-4965c9f2ea1e",
  "date_created": "2026-03-02T18:01:34.888000Z",
  "date_modified": "2026-03-02T18:01:34.888000Z",
  "file_hash": "69fc06d4d92385ca89901794535d28a62502e4c20dd9c3465054be47f8b314e9",
  "private": false,
  "record": {
    "abstract": "We investigate a stochastic version of a simple enzymatic reaction which\nfollows the generic Michaelis-Menten kinetics. At sufficiently high\nconcentrations of reacting species, the molecular fluctuations can be\napproximated as a realization of a Brownian dynamics for which the model\nreaction kinetics takes on the form of a stochastic differential equation.\nAfter eliminating a fast kinetics, the model can be rephrased into a form of a\none-dimensional overdamped Langevin equation. We discuss physical aspects of\nenvironmental noises acting in such a reduced system, pointing out the\npossibility of coexistence of dynamical regimes where noise-enhanced stability\nand resonant activation phenomena can be observed together.",
    "arxiv_id": "q-bio/0602015",
    "authors": [
      "A. Fiasconaro",
      "A. Ochab-Marcinek",
      "B. Spagnolo",
      "E. Gudowska-Nowak"
    ],
    "categories": [
      "q-bio.PE"
    ],
    "doi": "10.1103/PhysRevE.74.041904",
    "journal_ref": "Physical Review E 74, 041904 (2006)",
    "title": "Co-occurrence of resonant activation and noise-enhanced stability in a   model of cancer growth in the presence of immune response",
    "url": "https://arxiv.org/abs/q-bio/0602015"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "38ecd426-ae4f-48cb-99bf-056cffbece83",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}