dorsal/arxiv
View SchemaSystemic lupus erythematosus in African-American women: Cognitive physiological modules, autoimmune disease, and structured psychosocial stress
| Authors | Rodrick Wallace |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0311028 |
| URL | https://arxiv.org/abs/q-bio/0311028 |
Abstract
Examining elevated rates of systemic lupus erythematosus in African-American women from perspectives of immune cognition suggests the disease constitutes an internalized physiological image of external structured psychosocial stress, a 'pathogenic social hierarchy' involving the synergism of racism and gender discrimination in the context of policy-driven social disintegration which has particularly affected ethnic minorities in the USA. The disorder represents the punctuated resetting of normal immune self-image to a self-attacking excited state, a process formally analogous to models of punctuated equilibrium in evolutionary theory. Both onset and progression of disease may be stratified by a relation to cyclic physiological responses which are long in comparison with heartbeat period: circadian, hormonal, and annual light/termperature cycles.
{
"annotation_id": "1e06d38e-7c2b-4d65-96ef-710a71ceec46",
"date_created": "2026-03-02T18:01:28.468000Z",
"date_modified": "2026-03-02T18:01:28.468000Z",
"file_hash": "edcef6652b798593841627fe4e722ecf8237b26bc11efcebbc75bac32fbcb03d",
"private": false,
"record": {
"abstract": "Examining elevated rates of systemic lupus erythematosus in African-American\nwomen from perspectives of immune cognition suggests the disease constitutes an\ninternalized physiological image of external structured psychosocial stress, a\n\u0027pathogenic social hierarchy\u0027 involving the synergism of racism and gender\ndiscrimination in the context of policy-driven social disintegration which has\nparticularly affected ethnic minorities in the USA. The disorder represents the\npunctuated resetting of normal immune self-image to a self-attacking excited\nstate, a process formally analogous to models of punctuated equilibrium in\nevolutionary theory. Both onset and progression of disease may be stratified by\na relation to cyclic physiological responses which are long in comparison with\nheartbeat period: circadian, hormonal, and annual light/termperature cycles.",
"arxiv_id": "q-bio/0311028",
"authors": [
"Rodrick Wallace"
],
"categories": [
"q-bio.NC",
"q-bio.MN"
],
"title": "Systemic lupus erythematosus in African-American women: Cognitive physiological modules, autoimmune disease, and structured psychosocial stress",
"url": "https://arxiv.org/abs/q-bio/0311028"
},
"schema_id": "dorsal/arxiv",
"source": {
"execution_id": "782f056b-68fd-4ffb-8f4c-a8f3d6d10ba9",
"id": "arXiv Dataset IDs",
"type": "Model",
"variant": "snapshot-2026-03-01",
"version": "0.1.0"
},
"user_id": 1000002
}