dorsal/arxiv
View SchemaSelective pressures on genomes in molecular evolution
| Authors | Charles Ofria, Christoph Adami, Travis C. Collier |
|---|---|
| Categories | |
| ArXiv ID | quant-ph/0301075 |
| URL | https://arxiv.org/abs/quant-ph/0301075 |
| DOI | 10.1016/S0022-5193(03)00062-6 |
| Journal | J. theor. Biol. 222 (2003) 477-483 |
Abstract
We describe the evolution of macromolecules as an information transmission process and apply tools from Shannon information theory to it. This allows us to isolate three independent, competing selective pressures that we term compression, transmission, and neutrality selection. The first two affect genome length: the pressure to conserve resources by compressing the code, and the pressure to acquire additional information that improves the channel, increasing the rate of information transmission into each offspring. Noisy transmission channels (replication with mutations) gives rise to a third pressure that acts on the actual encoding of information; it maximizes the fraction of mutations that are neutral with respect to the phenotype. This neutrality selection has important implications for the evolution of evolvability. We demonstrate each selective pressure in experiments with digital organisms.
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"abstract": "We describe the evolution of macromolecules as an information transmission\nprocess and apply tools from Shannon information theory to it. This allows us\nto isolate three independent, competing selective pressures that we term\ncompression, transmission, and neutrality selection. The first two affect\ngenome length: the pressure to conserve resources by compressing the code, and\nthe pressure to acquire additional information that improves the channel,\nincreasing the rate of information transmission into each offspring. Noisy\ntransmission channels (replication with mutations) gives rise to a third\npressure that acts on the actual encoding of information; it maximizes the\nfraction of mutations that are neutral with respect to the phenotype. This\nneutrality selection has important implications for the evolution of\nevolvability. We demonstrate each selective pressure in experiments with\ndigital organisms.",
"arxiv_id": "quant-ph/0301075",
"authors": [
"Charles Ofria",
"Christoph Adami",
"Travis C. Collier"
],
"categories": [
"quant-ph",
"cs.NE",
"nlin.AO",
"physics.bio-ph",
"q-bio.PE"
],
"doi": "10.1016/S0022-5193(03)00062-6",
"journal_ref": "J. theor. Biol. 222 (2003) 477-483",
"title": "Selective pressures on genomes in molecular evolution",
"url": "https://arxiv.org/abs/quant-ph/0301075"
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