dorsal/arxiv
View SchemaStudy of Non-Altered Colorectal Tissue by FT-Raman Spectroscopy
| Authors | P. O. Andrade, R. A. Bitar, K. Yassoyama, H. Martinho, A. M. E. Santo, P. M. Bruno, A. A. Martin |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0607001 |
| URL | https://arxiv.org/abs/q-bio/0607001 |
Abstract
FT-Raman spectroscopy was employed to study (in-vitro) non-altered human colorectal tissues aiming evaluate their spectral differences. The samples were collected from 39 patients, adding 144 spectra. The results enable one estabilish 3 well defined spectroscopic groups of what was consistently checked by statistical (clustering) and biological (histopathology) analysis. The similarity within each group was better than 90%. Groups 1 and 2 had 80% of similarity while presenting both 70% of similarity to group 3. All groups presented connective and epithelial tissues as histopathological characteristic. Group 1 differs from others by the presence of soft muscle while group 3 by presence of fatty tissue. Tissues from group 2 are composed by samples with connective and epithelial tissues. This study is very relevant in order to establish the non-altered or normal spectroscopic standard for future studies and applications on optical biopsy and diagnosis of colorectal cancer.
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"abstract": "FT-Raman spectroscopy was employed to study (in-vitro) non-altered human\ncolorectal tissues aiming evaluate their spectral differences. The samples were\ncollected from 39 patients, adding 144 spectra. The results enable one\nestabilish 3 well defined spectroscopic groups of what was consistently checked\nby statistical (clustering) and biological (histopathology) analysis. The\nsimilarity within each group was better than 90%. Groups 1 and 2 had 80% of\nsimilarity while presenting both 70% of similarity to group 3. All groups\npresented connective and epithelial tissues as histopathological\ncharacteristic. Group 1 differs from others by the presence of soft muscle\nwhile group 3 by presence of fatty tissue. Tissues from group 2 are composed by\nsamples with connective and epithelial tissues. This study is very relevant in\norder to establish the non-altered or normal spectroscopic standard for future\nstudies and applications on optical biopsy and diagnosis of colorectal cancer.",
"arxiv_id": "q-bio/0607001",
"authors": [
"P. O. Andrade",
"R. A. Bitar",
"K. Yassoyama",
"H. Martinho",
"A. M. E. Santo",
"P. M. Bruno",
"A. A. Martin"
],
"categories": [
"q-bio.TO",
"q-bio.BM"
],
"title": "Study of Non-Altered Colorectal Tissue by FT-Raman Spectroscopy",
"url": "https://arxiv.org/abs/q-bio/0607001"
},
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