{
  "annotation_id": "137c8126-41a5-47ee-bba4-ab4f3cec8d28",
  "date_created": "2026-03-02T18:01:35.364000Z",
  "date_modified": "2026-03-02T18:01:35.364000Z",
  "file_hash": "20c66d93c5338602485a4ee604a613afe3ebfc6f82d3601582090eb0842d5b7a",
  "private": false,
  "record": {
    "abstract": "Stretching of a protein by a fluid flow is compared to that in a force-clamp\napparatus. The comparison is made within a simple topology-based dynamical\nmodel of a protein in which the effects of the flow are implemented using\nLangevin dynamics. We demonstrate that unfolding induced by a uniform flow\nshows a richer behavior than that in the force clamp. The dynamics of unfolding\nis found to depend strongly on the selection of the amino acid, usually one of\nthe termini, which is anchored. These features offer potentially wider\ndiagnostic tools to investigate structure of proteins compared to experiments\nbased on the atomic force microscopy.",
    "arxiv_id": "q-bio/0610046",
    "authors": [
      "P. Szymczak",
      "Marek Cieplak"
    ],
    "categories": [
      "q-bio.BM"
    ],
    "doi": "10.1063/1.2358346",
    "title": "Stretching of proteins in a uniform flow",
    "url": "https://arxiv.org/abs/q-bio/0610046"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "8f5183fd-9d59-40d2-bdb9-802da28527fc",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}