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As at 30 September 2026

INSTITUTIONAL NORTH AMERICAN INDEX

OPPORTUNITIES FUND

I Acc ISIN GB00B00K2Z88

Marketing communication Page 1 / 4

Fund details

Inception date 24 February 2006 Total net assets 526.26m Asset class Equities Domicile United Kingdom Structure OEIC Base currency GBP Index Solactive GBS North America Customised Index Peer group IA North America Equity For benchmark/usage description, refer to Additional fund information on page 3 . Share class information

Inception date 24 February 2006 Distribution type Accumulation Net Distribution frequency Biannually Historic yield 0.50% Currency GBP Minimum initial investment 500,000

The Historic Yield does not include any preliminary charge and investors may be subject to tax on their distributions. Portfolio management

Diversified Alternatives Team

Manager since 2006

Ratings

Overall Morningstar Rating TM     As of 30/09/2026 Morningstar Medalist Rating TM Effective 31/08/2026 Analyst - Driven%: 10.00 Data Coverage%: 94.00 n/a For more information, refer to page 3 .

Investment objective The Fund aims to provide a return, of at least that achieved by the Solactive GBS North America customised Index (the Reference Index) +0.5% per annum, before the deduction of charges, over any 5 year period. For the fund’s investment policy, refer to the Additional fund information on page 3 . Past performance does not predict future returns.

Performance (%)

Returns

Cumulative Annualised

1 Month

3 Month YTD

1 Year

3 Year

5 Year

10 Year

Since inception (30/09/04) I Acc (Net) 1.50 3.08 13.12 17.22 19.35 12.93 14.49 — Index 1.57 2.32 13.83 16.92 19.52 13.56 14.68 12.51 Peer Group 0.23 0.53 11.14 13.50 15.78 10.37 12.69 10.73 I Acc (Gross) — — — — — 13.33 14.90 — Target — — — — — 14.13 15.02 12.66

Cumulative growth – GBP

30 Sep 2021 — 30 Sep 2026

━━

Institutional North American Index Opportunities Fund I Acc (Net)

━━

Solactive GBS North America customised Index ━━ IA North America

12 month rolling Sep 2025 Sep 2026

Sep 2024 Sep 2025

Sep 2023 Sep 2024

Sep 2022 Sep 2023

Sep 2021 Sep 2022 I Acc (Net) 17.22 18.08 22.85 7.00 0.95 Index 16.92 18.25 23.50 10.85 - 0.23 Peer Group 13.50 13.41 20.57 8.10 - 2.39 Performance is on a net of fees basis, with gross income reinvested. Source: at 30/09/26. © 2026 Morningstar, Inc. All rights reserved. The information contained herein: (1) is proprietary to Morningstar and/or its content providers; (2) may not be copied or distributed; and (3) is not warranted to be accurate, complete, or timely. Neither Morningstar nor its content providers are responsible for any damages or losses arising from any use of this information. Past performance does not predict future returns . Performance/performance target related data will display only where relevant to the share class inception date and annualised target time period. The value of an investment and the income from it can fall as well as rise and you may not get back the amount originally invested. Source for target returns (where applicable) - Janus Henderson Investors.

-20

100

Sep-21 Sep-22 Sep-23 Sep-24 Sep-25 Sep-26

Page 2

Institutional North American Index Opportunities Fund I Acc (as at 30/09/26)

Page 2 / 4

Top sectors (%)

Top countries (%)

Codes ISIN GB00B00K2Z88 Bloomberg HENGEFI SEDOL B00K2Z8 WKN A0MS0U Valoren 1962373 n/a n/a Fees & charges (%) Annual management charge (AMC) 0.30 Ongoing charge (OCF) 0.37 All ongoing charges stated are as per latest published report and accounts. Fund charges will impact the value of your investment. In particular, the ongoing charges applicable to each fund will dilute investment performance, particularly over time. For further explanation of charges please visit our Fund Charges page at www.janushenderson.com. Un der some circumstances initial charges may apply. Please refer to the Prospectus for more details.

Technology Financials Consumer Discretionary Industrials Health Care Energy Consumer Staples Telecommunications Utilities Basic Materials Cash

Fund 45.72 17.13 11.63 9.99 8.45 4.16 3.27 2.29 2.16 1.85

- 6.83

Index 45.34 10.30 11.35 9.86 8.32 3.97 3.28 2.23 2.06 1.85

—

United States Luxembourg Canada United Kingdom South Africa China Index Derivatives

Fund 96.06 6.73 4.72 0.07 0.07 0.04

- 0.86

Index 95.43

— 4.50

— 0.07

— —

Characteristics Number of holdings: Equity issues 541 Weighted average market cap 891.45bn Price - to - book ratio 4.86 Price - to - earnings ratio 18.63 n/a n/a Risk statistics (3 years) Fund Index Beta 1.03 — Standard deviation 13.43 12.19 Sharpe ratio 1.05 1.17 Tracking error 4.56 —

Top holdings (%) Fund NVIDIA 7.92 Apple 7.13 Janus Henderson Global Multi - Strategy Fund Z2 Husd 6.73 Microsoft 5.64 Alphabet 5.61 Amazon.com 3.59 Broadcom 2.45 Meta Platforms 2.38 Micron Technology 1.80 Tesla 1.63 Total 44.88 References made to individual securities do not constitute a recommendation to buy, sell or hold any security, investment strategy or market sector, and should not be assumed to be profitable. Janus Henderson Investors, its affiliated advisor, or its employees, may have a position in the securities mentioned.

Market capitalisation of equity holdings (%) Fund Index Over £1T 36.49 36.30 £500B to £1T 9.67 9.63 £100B to £500B 26.71 26.81 £50B to £100B 14.38 14.29 £25B to £50B 8.84 8.54 Under £25B 4.73 4.43

Page 3

Institutional North American Index Opportunities Fund I Acc (as at 30/09/26)

Page 3 / 4

Additional fund information

Tax assumptions and reliefs depend upon an investor’s particular circumstances and may be subject to change. Please note the performance target is to be achieved over a specific annualised time period. Refer to the performance target wording within the objective. From 31 Oct ober 2020, the Benchmark changed to the Solactive GBS North America customised Index from the FTSE customi sed North American Index, the Investment Objective, Performance Target Index & Policy also changed. Past performance shown before this date was achieved under circumstances that no longer apply. Fund size at 12pm on last business day of month. Please note: due to rounding the figures in the holdings breakdowns may not add up to 100%. Performance for the share class is calculated at 12pm and performance of the index is calculated as at close of business. Not e that any differences among portfolio securities c urrencies, share class currencies and costs to be paid or represented in currencies other than your home currency will expose you to currency risk. Costs and returns may increase or decrease as a result of currency and exchange rate fluctuation s. Investmen t into the fund will acquire units/shares of the fund itself and not the underlying assets owned by the fund. Cash balances and exposures are based on settled and unsettled trades as at the reporting date. The Solactive GBS North America customised Inde x is a measure of the combined performance of large and medium sized companies from North American stock markets. It forms the basis of the Fund’s performance target. The Investment Association (IA) groups funds with similar geographic and/or investment remit into sectors. The Fund's ranking within the sector (as calculated by a number of data providers) can be a useful performance comparison against other funds with similar aims. Investment policy The Fund invests at least 80% of its assets in shares (also known as equities) of companies, of any size, in any industry, which are included in the Reference Index. The Fund may also invest in other assets including bonds, Collective Investment Schemes (including those man aged by Janus Hend erson), cash and money market instruments, and may use derivatives (complex financial instruments), including total return sw aps, with the aim of making investment gains in line with the Fund's objective, to reduce risk or to manage the Fund more efficient ly. The Fund is in part passively managed as its investments in at least 80% of its assets within shares of the Reference Index seek to replicate the components of the Reference Index. The components of the Reference Index will not be identically replicate d, and this can lead to differences in performance. The 'customised' aspect of the Reference Index indicates that its performance is adjusted to reflect the actual tax rates applicable to dividend income rece ived by the fund. As an additional means of asse ssing the performance of the Fund, the IA North America sector average, which is based on a peer group of broadly similar funds, may also provide a useful comparator. Investment strategy The Investment Manager seeks to reflect the performance of the Reference Index while making use of investment strategies aimed at enhancing returns whilst taking a low level of additional risk. Some strategies used by the Investment Manager seek to generate returns based o n differences in the prices of securities iss ued by, or associated with, companies that form part of the Reference Index. They can include, but are not limited to, liquid ity strategies (investing in 'blocks of stock' at discounted prices), and relative value strategies (taking advantage of difference s between the prices of securities related to the same company). Other strategies may not be related specifically to the Reference Index and can be outside North Americ a to the extent that those strategies remain consistent with the Fund’s Investment Objec tive and Policy as set out above. Further details explaining the investment strategies are available on the Funds’ pages on our website (www.janushenderson.com). Fund specific risks Shares can lose value rapidly, and typically involve higher risks than bonds or money market instruments. The value of your investment may fall as a result. SPACs are shell companies set up to acquire businesses. They are complex and often lack the transparency of establish ed companies, and therefore present greater risk s to investors. High exposure to a particular country or geographical region carries a higher level of risk than a more broad ly diversified portfolio. If the Fund holds assets in currencies other than the base currency of the Fund, or you invest in a sh are /unit class of a different currency to the Fund (unless hedged, i.e. seeks to mitigate exchange rate movements between the share/unit class currency and the base currency of the Fund), the value of your investment may be impacted by changes in exchange rat es. Derivatives may be used to help achieve the investment objective. This can result in leverage (higher levels of debt), which can magnify an investment outcome. Gains or losses may therefore be greater than the cost of the derivative. Derivatives also i ntroduce other risks, in particular, that a derivative counterparty may not meet its contractual obligations. Securities could become hard to value or to sell at a desired time and price, especially in extreme market conditions when as set prices may be fal ling, increasing the risk of investment losses. Returns from investing in index enhancing opportunities may vary over time relative to the Reference Index. The managers do not, however, seek to take high levels of risk and investors should therefore expect the typical level of enhancement of returns to be low. Strategies aimed at enhancing returns depend on the manager skill and decision - making; this therefore carries the risk that a Fund may underperform its Reference Index if the strategy used is unsucces sful. Additionally, depending on the share/unit class you invest in and any costs you pay to third parties to invest in our funds, after the deduction of ongoing charges and transaction costs your investment may underperform the Ref erence Index. Losses cou ld be incurred if a counterparty became unwilling or unable to meet its obligations, or as a result of failure or delay in op erational processes or the failure of a third party provider. Source for fund ratings/awards Overall Morningstar Rating™ is a measure of a fund's risk - adjusted return, relative to similar funds. Fund share classes are rated from 1 to 5 stars, with the best performers receiving 5 stars and the worst performers receiving a single star. Where available, over all Morningstar Rating™ is shown for share classes achieving a rating of 4 or 5 stars. Morningstar Medalist Rating™ Ratings should not be taken as a recommendation. For more detailed information about Morningstar Ratings, including its methodology, please go to https://shareholders.morningstar.com/investor relations/governance/Compliance -- Disclosure/default.aspx .

Page 4

Institutional North American Index Opportunities Fund I Acc (as at 30/09/26)

Page 4 / 4

Glossary

Beta Beta measures how a fund or security moves in relationship to the overall market. A market has a beta of 1. If the fund/security’s beta is more than 1, it moves more than the market, while a beta lower than 1 means it moves to a lesser extent than the market. A negative beta could mean the fund/security moves in the opposite direction to the market. Historic Yield The Historic Yield reflects distributions declared over the past 12 months as a percentage of the mid - market share price, as at the date shown. Pric e - to - book (P/B) ratio A financial ratio used to value a company's shares. It is calculated by dividing a company’s market value (share price) by th e book value of its equity (value of the company's assets on its balance sheet). A P/B value <1 can indicate a potentially undervalued company or a declining business. The higher the P/B ratio, the higher the premium the market is willing to pay for the company above the book (balance sheet) value of it s assets. Price - to - earnings (P/E) ratio A popular ratio used to value a company’s shares, compared to other stocks, or a benchmark index. It is calculated by dividing the current share p rice by its earnings per share. Sharpe ratio This measures a portfolio's risk - adjusted performance. A high Sharpe ratio indicates a better risk - adjusted return. The ratio is designed to measure how far a portfolio’s return can be attributed to fund manager skill as opposed to excessive risk taking. Standard deviation A statistic that measures the variation or dispersion of a set of values/data. A low standard deviation shows the values tend to be close to the mean while a high standard deviation indicates the values are more spread out. In terms of valuing investments, standard deviation can p rovide a gauge of the historical volatil ity of an investment. Swaps A derivative contract between two parties where pre - determined cash flows of two financial instruments are exchanged. Swaps can help to hedge risk and minimise uncertainty; for example currency swaps can be used to minimise for eign currency exposure. Tracking error This measures how far a portfolio’s actual performance differs from its benchmark index. The lower the number, the more close ly it resembles the index. Weighted average market cap The average market capitalisation o f a holding, weighted by the size of that position in a portfolio or index.

FOR MORE INFORMATION PLEASE VISIT JANUSHENDERSON.COM

Unless otherwise indicated all figures sourced from Morningstar, Datastream, BNP Paribas and Janus Henderson Investors. Marketing Communication. Past performance does not predict future returns. Please note the views, opinions and forecasts expressed in this document ar e based on Janus Henderson Investors research, analysis and house views at the time o f publication. Third party data is believed to be reliable, but its completeness and accuracy is not guaranteed. Please read all scheme documents before investing. Before entering into an investment agreement i n respect of an investment referred to in this document, you should consult your own professional and/or investment adviser. The value of an investment and the income from it can fall as well as rise and you may not get back the amount originally invested. Tax assumptions and reliefs depend upon an in vestor’s particular circumstances and may change if those circumstances or the law change. If you invest through a third party provider you are a dvised to consult them directly as charges, performance and terms and conditions may differ materially than tho se shown on this document. Nothing in this document is intended to or should be construed as advice. This communication does not constitute an offer or a recommendation to sell or purchase any investment. It does not form part of any contract for the sale or purchase of any investment. Any investment application will be made solely on the basis of the information contained in the Prospectus (including all relevant covering documents), which will contain investment restrictions. This doc ument is intended as a summary only and potential investors must read the prospectus, and where relevant, the key investor information document befo re investing. We may record telephone calls for our mutual protection, to improve customer service and for regulatory record keep ing purposes. Issued in UK by Janus Henderson Investors. Janus Henderson Investors is the name under which investment products and services are provided by Janus Henderson Investors International Limited (reg no. 3594615), Janus Henderson Investors UK Limi ted (reg. no. 906355), Janus Henderson Fund Management UK Limited (reg. no. 2678531), Tabula Investment Management Limited (reg. no. 11286661), (each registered in England and Wales at 201 Bishopsg ate, London EC2M 3AE and regulated by the Financial Conduct Authority) and Janus Henderson Investors Europe S.A. (reg no. B22848 at 78, Avenue de la Liberté, L - 1930 Luxembourg, Luxembourg and regulated by the Commission de Surveillance du Secteur Financier). In Ireland the Facilities Agent is BNP Paribas Fund Admi nistration Services (Ireland) Limited. Janus Henderson® and any other trademarks used herein are trademarks of Janus Henderso n Group Ltd. or one of its subsidiaries. © Janus Henderson Group Ltd.

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