dorsal/arxiv
View SchemaComparative analysis of protein structure using multiscale additive functionals
| Authors | Marconi Soares Barbosa, Rinaldo Wander Montalvao, Tom Blundell, Luciano da Fontoura Costa |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0701019 |
| URL | https://arxiv.org/abs/q-bio/0701019 |
Abstract
This work reports a new methodology aimed at describing characteristics of protein structural shapes, and suggests a framework in which to resolve or classify automatically such structures into known families. This new approach to protein structure characterization is based on elements of integral geometry using biologically relevant measurements of shape and considering them on a multi-scale representation which align the proposed methodology to the recently reported "tube picture" of a protein structure as a minimal representation model. The method has been applied with good results to a subset of protein structures known to be especially challenging to revert into families, confirming the potential of the proposed method for accurate structure classification.
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"date_created": "2026-03-02T18:01:35.815000Z",
"date_modified": "2026-03-02T18:01:35.815000Z",
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"abstract": "This work reports a new methodology aimed at describing characteristics of\nprotein structural shapes, and suggests a framework in which to resolve or\nclassify automatically such structures into known families. This new approach\nto protein structure characterization is based on elements of integral geometry\nusing biologically relevant measurements of shape and considering them on a\nmulti-scale representation which align the proposed methodology to the recently\nreported \"tube picture\" of a protein structure as a minimal representation\nmodel. The method has been applied with good results to a subset of protein\nstructures known to be especially challenging to revert into families,\nconfirming the potential of the proposed method for accurate structure\nclassification.",
"arxiv_id": "q-bio/0701019",
"authors": [
"Marconi Soares Barbosa",
"Rinaldo Wander Montalvao",
"Tom Blundell",
"Luciano da Fontoura Costa"
],
"categories": [
"q-bio.QM",
"cond-mat.stat-mech",
"physics.bio-ph"
],
"title": "Comparative analysis of protein structure using multiscale additive functionals",
"url": "https://arxiv.org/abs/q-bio/0701019"
},
"schema_id": "dorsal/arxiv",
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