dorsal/arxiv
View SchemaGenetic Paralog Analysis and Simulations
| Authors | Stanislaw Cebrat, Jan P. Radomski, Dietrich Stauffer |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0312027 |
| URL | https://arxiv.org/abs/q-bio/0312027 |
Abstract
Using Monte Carlo methods, we simulated the effects of bias in generation and elimination of paralogs on the size distribution of paralog groups. It was found that the function describing the decay of the number of paralog groups with their size depends on the ratio between the probability of duplications of genes and their deletions, which corresponds to different selection pressures on the genome size. Slightly different slopes of curves describing the decay of the number of paralog groups with their size were also observed when the threshold of homology between paralogous sequences was changed.
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"abstract": "Using Monte Carlo methods, we simulated the effects of bias in generation and\nelimination of paralogs on the size distribution of paralog groups. It was\nfound that the function describing the decay of the number of paralog groups\nwith their size depends on the ratio between the probability of duplications of\ngenes and their deletions, which corresponds to different selection pressures\non the genome size. Slightly different slopes of curves describing the decay of\nthe number of paralog groups with their size were also observed when the\nthreshold of homology between paralogous sequences was changed.",
"arxiv_id": "q-bio/0312027",
"authors": [
"Stanislaw Cebrat",
"Jan P. Radomski",
"Dietrich Stauffer"
],
"categories": [
"q-bio.GN"
],
"title": "Genetic Paralog Analysis and Simulations",
"url": "https://arxiv.org/abs/q-bio/0312027"
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