{
  "annotation_id": "0d6e5b08-2176-4c67-b01b-e0b72e0cf9e4",
  "date_created": "2026-03-02T18:01:32.177000Z",
  "date_modified": "2026-03-02T18:01:32.177000Z",
  "file_hash": "c6e30474dafe7d55404bba24b35c060efeba25814335ba2e0926dcdd89b8bb92",
  "private": false,
  "record": {
    "abstract": "Gene sequences in the vicinity of splice sites are found to possess\ndinucleotide periodicities, especially RR and YY, with the period close to the\npitch of nucleosome DNA. This confirms previously reported finding about\npreferential positioning of splice junctions within the nucleosomes. The RR and\nYY dinucleotides oscillate counterphase, i.e., their respective preferred\npositions are shifted about half-period one from another, as it was observed\nearlier for AA and TT dinucleotides. Species specificity of nucleosome\npositioning DNA pattern is indicated by predominant use of the periodical\nGG(CC) dinucleotides in human and mouse genes, as opposed to predominant AA(TT)\ndinucleotides in Arabidopsis and C.elegans.\n  Keywords: chromatin; gene splicing; intron; exon; dinucleotide; periodical\npattern",
    "arxiv_id": "q-bio/0411024",
    "authors": [
      "Simon Kogan",
      "Edward N. Trifonov"
    ],
    "categories": [
      "q-bio.GN"
    ],
    "title": "Gene splice sites correlate with nucleosome positions",
    "url": "https://arxiv.org/abs/q-bio/0411024"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "c383bf59-7a24-4f6a-ade9-9b82144a8a91",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}