dorsal/arxiv
View SchemaNeural Architecture for Fast and Reliable Coagulation Assessment in Clinical Settings: Leveraging Thromboelastography
| Authors | Yulu Wang, Ziqian Zeng, Jianjun Wu, Zhifeng Tang |
|---|---|
| Categories | |
| ArXiv ID | 2601.07618vv1 |
| URL | https://arxiv.org/abs/2601.07618 |
| License | http://arxiv.org/licenses/nonexclusive-distrib/1.0/ |
Abstract
In an ideal medical environment, real-time coagulation monitoring can enable early detection and prompt remediation of risks. However, traditional Thromboelastography (TEG), a widely employed diagnostic modality, can only provide such outputs after nearly 1 hour of measurement. The delay might lead to elevated mortality rates. These issues clearly point out one of the key challenges for medical AI development: Mak-ing reasonable predictions based on very small data sets and accounting for variation between different patient populations, a task where conventional deep learning methods typically perform poorly. We present Physiological State Reconstruc-tion (PSR), a new algorithm specifically designed to take ad-vantage of dynamic changes between individuals and to max-imize useful information produced by small amounts of clini-cal data through mapping to reliable predictions and diagnosis. We develop MDFE to facilitate integration of varied temporal signals using multi-domain learning, and jointly learn high-level temporal interactions together with attentions via HLA; furthermore, the parameterized DAM we designed maintains the stability of the computed vital signs. PSR evaluates with 4 TEG-specialized data sets and establishes remarkable perfor-mance -- predictions of R2 > 0.98 for coagulation traits and error reduction around half compared to the state-of-the-art methods, and halving the inferencing time too. Drift-aware learning suggests a new future, with potential uses well be-yond thrombophilia discovery towards medical AI applica-tions with data scarcity.
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"abstract": "In an ideal medical environment, real-time coagulation monitoring can enable early detection and prompt remediation of risks. However, traditional Thromboelastography (TEG), a widely employed diagnostic modality, can only provide such outputs after nearly 1 hour of measurement. The delay might lead to elevated mortality rates. These issues clearly point out one of the key challenges for medical AI development: Mak-ing reasonable predictions based on very small data sets and accounting for variation between different patient populations, a task where conventional deep learning methods typically perform poorly. We present Physiological State Reconstruc-tion (PSR), a new algorithm specifically designed to take ad-vantage of dynamic changes between individuals and to max-imize useful information produced by small amounts of clini-cal data through mapping to reliable predictions and diagnosis. We develop MDFE to facilitate integration of varied temporal signals using multi-domain learning, and jointly learn high-level temporal interactions together with attentions via HLA; furthermore, the parameterized DAM we designed maintains the stability of the computed vital signs. PSR evaluates with 4 TEG-specialized data sets and establishes remarkable perfor-mance -- predictions of R2 \u003e 0.98 for coagulation traits and error reduction around half compared to the state-of-the-art methods, and halving the inferencing time too. Drift-aware learning suggests a new future, with potential uses well be-yond thrombophilia discovery towards medical AI applica-tions with data scarcity.",
"arxiv_id": "2601.07618",
"authors": [
"Yulu Wang",
"Ziqian Zeng",
"Jianjun Wu",
"Zhifeng Tang"
],
"categories": [
"cs.LG",
"cs.AI"
],
"license": "http://arxiv.org/licenses/nonexclusive-distrib/1.0/",
"title": "Neural Architecture for Fast and Reliable Coagulation Assessment in Clinical Settings: Leveraging Thromboelastography",
"url": "https://arxiv.org/abs/2601.07618",
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