dorsal/arxiv
View SchemaSurface plasmon resonance study of the actin-myosin sarcomeric complex and tubulin dimers
| Authors | Hans A. Schuessler, Alexander A. Kolomenskii, Andreas Mershin, D. V. Nanopoulos |
|---|---|
| Categories | |
| ArXiv ID | quant-ph/0302159 |
| URL | https://arxiv.org/abs/quant-ph/0302159 |
| DOI | 10.1080/09500340308233570 |
| Journal | J. Modern Optics No. 15-17, p2381-2391 (2003) |
Abstract
Biosensors based on the principle of surface plasmon resonance (SPR) detection were used to measure biomolecular interactions in sarcomeres and changes of the dielectric constant of tubulin samples with varying concentration. At SPR, photons of laser light efficiently excite surface plasmons propagating along a metal (gold) film. This resonance manifests itself as a sharp minimum in the reflection of the incident laser light and occurs at a characteristic angle. The dependence of the SPR angle on the dielectric permittivity of the sample medium adjacent to the gold film allows the monitoring of molecular interactions at the surface. We present results of measurements of cross-bridge attachment/detachment within intact mouse heart muscle sarcomeres and measurements on bovine tubulin molecules pertinent to cytoskeletal signal transduction models.
{
"annotation_id": "04b8d79e-519e-402c-b7ff-dea1fc0af6ed",
"date_created": "2026-03-02T18:01:55.656000Z",
"date_modified": "2026-03-02T18:01:55.656000Z",
"file_hash": "bd7ec1ea604a447c06e915ccbcea64cee19d54210a5ceff3e77578590ee725bf",
"private": false,
"record": {
"abstract": "Biosensors based on the principle of surface plasmon resonance (SPR)\ndetection were used to measure biomolecular interactions in sarcomeres and\nchanges of the dielectric constant of tubulin samples with varying\nconcentration. At SPR, photons of laser light efficiently excite surface\nplasmons propagating along a metal (gold) film. This resonance manifests itself\nas a sharp minimum in the reflection of the incident laser light and occurs at\na characteristic angle. The dependence of the SPR angle on the dielectric\npermittivity of the sample medium adjacent to the gold film allows the\nmonitoring of molecular interactions at the surface. We present results of\nmeasurements of cross-bridge attachment/detachment within intact mouse heart\nmuscle sarcomeres and measurements on bovine tubulin molecules pertinent to\ncytoskeletal signal transduction models.",
"arxiv_id": "quant-ph/0302159",
"authors": [
"Hans A. Schuessler",
"Alexander A. Kolomenskii",
"Andreas Mershin",
"D. V. Nanopoulos"
],
"categories": [
"quant-ph"
],
"doi": "10.1080/09500340308233570",
"journal_ref": "J. Modern Optics No. 15-17, p2381-2391 (2003)",
"title": "Surface plasmon resonance study of the actin-myosin sarcomeric complex and tubulin dimers",
"url": "https://arxiv.org/abs/quant-ph/0302159"
},
"schema_id": "dorsal/arxiv",
"source": {
"execution_id": "26bd992e-c8d8-45ad-a915-57af9c593fb4",
"id": "arXiv Dataset IDs",
"type": "Model",
"variant": "snapshot-2026-03-01",
"version": "0.1.0"
},
"user_id": 1000002
}