{
  "annotation_id": "0441e0a9-8a22-4b3e-8caa-16fd71456a8d",
  "date_created": "2026-03-02T18:01:31.425000Z",
  "date_modified": "2026-03-02T18:01:31.425000Z",
  "file_hash": "8de05629b71adf0b48261e385c3545cf9db567e013e02e33b55bc7b63267614a",
  "private": false,
  "record": {
    "abstract": "We present a method to quantify spatial fluctuations of the substitution rate\non different length scales throughout genomes of eukaryotes. The fluctuations\non large length scales are found to be predominantly a consequence of a\ncoarse-graining effect of fluctuations on shorter length scales. This is\nverified for both the mouse and the human genome. We also found that both\nspecies show similar standard deviation of fluctuations even though their mean\nsubstitution rate differs by a factor of two. Our method furthermore allows to\ndetermine time-resolved substitution rate maps from which we can compute\nauto-correlation functions in order to quantify how fast the spatial\nfluctuations in substitution rate change in time.",
    "arxiv_id": "q-bio/0403044",
    "authors": [
      "H. H. von Gr\u00fcnberg",
      "M. Kollmann"
    ],
    "categories": [
      "q-bio.GN",
      "q-bio.PE"
    ],
    "doi": "10.1103/PhysRevLett.93.208102",
    "title": "Variations in Substitution Rate in Human and Mouse Genomes",
    "url": "https://arxiv.org/abs/q-bio/0403044"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "0e871394-513a-45cd-b688-a0a46bf35bac",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}