dorsal/arxiv
View SchemaDynamics and coding of a biologically-motivated network
| Authors | Carlos Aguirre, Joao Martins, R. Vilela Mendes |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0407031 |
| URL | https://arxiv.org/abs/q-bio/0407031 |
| Journal | Int. Journal of Bifurcation and Chaos 16 (2006) 383-394 |
Abstract
A four-node network consisting of a negative loop controlling a positive one is studied. It models some of the features of the p53 gene network. Using piecewise linear dynamics with thresholds, the allowed dynamical classes are fully characterized and coded. The biologically relevant situations are identified and conclusions drawn concerning the effectiveness of the p53 network as a tumour inhibitor mechanism.
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"abstract": "A four-node network consisting of a negative loop controlling a positive one\nis studied. It models some of the features of the p53 gene network. Using\npiecewise linear dynamics with thresholds, the allowed dynamical classes are\nfully characterized and coded. The biologically relevant situations are\nidentified and conclusions drawn concerning the effectiveness of the p53\nnetwork as a tumour inhibitor mechanism.",
"arxiv_id": "q-bio/0407031",
"authors": [
"Carlos Aguirre",
"Joao Martins",
"R. Vilela Mendes"
],
"categories": [
"q-bio.MN"
],
"journal_ref": "Int. Journal of Bifurcation and Chaos 16 (2006) 383-394",
"title": "Dynamics and coding of a biologically-motivated network",
"url": "https://arxiv.org/abs/q-bio/0407031"
},
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