dorsal/arxiv
View SchemaIs the intrinsic disorder of proteins the cause of the scale-free architecture of protein-protein interaction networks?
| Authors | Santiago Schnell, Santo Fortunato, Sourav Roy |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0606029 |
| URL | https://arxiv.org/abs/q-bio/0606029 |
Abstract
In protein-protein interaction networks certain topological properties appear to be recurrent: networks maps are considered scale-free. It is possible that this topology is reflected in the protein structure. In this paper we investigate the role of protein disorder in the network topology. We find that the disorder of a protein (or of its neighbors) is independent of its number of protein-protein interactions. This result suggests that protein disorder does not play a role in the scale-free architecture of protein networks.
{
"annotation_id": "022d57c4-5643-4bfa-a8e4-cdbf5489e882",
"date_created": "2026-03-02T18:01:35.336000Z",
"date_modified": "2026-03-02T18:01:35.336000Z",
"file_hash": "492cf4c4d6c1b4cbd100cd21e05aee17c62ff4b5a3bdba5227b57e2dcf7bb798",
"private": false,
"record": {
"abstract": "In protein-protein interaction networks certain topological properties appear\nto be recurrent: networks maps are considered scale-free. It is possible that\nthis topology is reflected in the protein structure. In this paper we\ninvestigate the role of protein disorder in the network topology. We find that\nthe disorder of a protein (or of its neighbors) is independent of its number of\nprotein-protein interactions. This result suggests that protein disorder does\nnot play a role in the scale-free architecture of protein networks.",
"arxiv_id": "q-bio/0606029",
"authors": [
"Santiago Schnell",
"Santo Fortunato",
"Sourav Roy"
],
"categories": [
"q-bio.GN",
"q-bio.MN"
],
"title": "Is the intrinsic disorder of proteins the cause of the scale-free architecture of protein-protein interaction networks?",
"url": "https://arxiv.org/abs/q-bio/0606029"
},
"schema_id": "dorsal/arxiv",
"source": {
"execution_id": "79880f9f-e304-4020-aa93-c7549d6d85d4",
"id": "arXiv Dataset IDs",
"type": "Model",
"variant": "snapshot-2026-03-01",
"version": "0.1.0"
},
"user_id": 1000002
}